منابع مشابه
molecular interactions of lncrnas: cellular fate determination and tissue regeneration
lncrnas (long non-coding rnas) are responsible to control the degradation process, rna stability, orchestration, inhibition, transcription and histone modification etc. these rnas have been termed as the key agents of several mechanisms such as development, organogenesis and regeneration of damaged tissues etc. they interact with a number of partner molecules either protein, rnas or dnas and co...
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1.1 Defining differentiation and cell fate in cancer In the setting of embryonic development, terms such as “cell fate“ and “cellular differentiation“ are relatively easy to grasp, since they refer to a straightforward linear model whereby progenitor cells give rise sequentially to various distinct and identifiable lineages, eventually resulting in a terminally differentiated cell that has unti...
متن کاملHuman Intersex
London: E. & S. Livingstone, 1962. THE extraordinar-y developmenit of research aInd increase in knowledge of sexual alnomalies and human genetics, in the last decade, has outdistaniced most clinicians leavinlg us sadly bewildered. The steady outpouring of papers has literally svamped us aIId if we are to gain any insight into this rapidly increasing field of medical understanding Nve are depeni...
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Complete trisomy 22, with or without mosaicism, has been reported as a distinct syndrome. In this report an infant is described who was externally male but with female rudimentary internal organs and whose karyotype was 47,XX+22.
متن کاملA genetic analysis of intersex, a gene regulating sexual differentiation in Drosophila melanogaster females.
Sex-type in Drosophila melanogaster is controlled by a hierarchically acting set of regulatory genes. At the terminus of this hierarchy lie those regulatory genes responsible for implementing sexual differentiation: genes that control the activity of target loci whose products give rise to sexually dimorphic phenotypes. The genetic analysis of the intersex (ix) gene presented here demonstrates ...
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ژورنال
عنوان ژورنال: Cell Death & Disease
سال: 2021
ISSN: 2041-4889
DOI: 10.1038/s41419-021-03676-x